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目的探讨细胞学联合肿瘤标志物鉴别非典型良恶性胸水。方法 2009年1月至2011年3月经胸水细胞学检测,提示有非典型细胞的胸水患者198例,经明确诊断后分为良性胸水病例102例,恶性胸水病例96例进行肿瘤标志物检测。结果两组病例进行肿瘤标志物CEA,CA-199,CA-125,CA-153检测,统计并进行比较差异有统计学意义(P<0.05)。结论细胞学联合肿瘤标志物能够及时的对良恶性胸水进行鉴别,为临床诊断提供有力的佐证。
Objective To investigate the differentiation of atypical benign and malignant pleural effusions with cytology combined with tumor markers. Methods From January 2009 to March 2011, pleural effusion cytology test revealed 198 patients with atypical pleural effusions. After definitive diagnosis, 102 patients were divided into benign pleural effusions and 96 patients with malignant pleural effusions were tested for tumor markers. Results The tumor markers CEA, CA-199, CA-125, and CA-153 were detected in the two groups of patients. Statistically significant difference was statistically significant (P<0.05). Conclusion The combination of cytology and tumor markers can identify benign and malignant pleural effusions in a timely manner and provide strong evidence for clinical diagnosis.