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1978～1986年广州市先后发生了由登革热病毒4个血清型的4次登革热流行,每型均未重复出现。年发病率在2～57/10万,病死率在0～0.33％,流行主要见于市区边缘居民区,市区呈散发。病例以20～39岁年龄多见,男女大致相等,职业分布与城市人口职业构成相似,不同型登革热病毒感染的临床症状表现有差异,但4次流行中病人血清补结试验均呈初次感染表现。在4次流行中有3次可以追溯到明显外来的传染来源,每次流行均起于当年6～7月,高峰多为9月、12月流行终止,从未跨年度。鉴于本病尚无可靠的快速诊断的方法,故有必要加强疫情监测工作,警惕本病的再度传入。从1978年广东省佛山市出现解放后首次流行登革热以来,广州市区当年亦受到影响,有病例散发和局部小型爆发,1980年海南岛发生登革热大流行,同年传入广州相继出现流行。到1986年止,先后共发生四次流行。现将登革热在我市的发病特点报告于下。
From 1978 to 1986, four dengue epidemics of four serotypes of dengue virus occurred successively in Guangzhou City, each of which did not appear repeatedly. The annual incidence rate was between 2 and 57 per 100 000 and the case fatality rate was between 0 and 0.33%. The prevalence was mainly found in residential areas on the fringe of urban areas and the urban area was distributed. Cases of 20 to 39 years of age more common, roughly equal between men and women, occupational distribution and occupational composition similar to the urban population, different types of clinical manifestations of dengue virus infection showed differences, but the four epidemic patients with serum complement test showed the initial infection performance . In 4 out of 3 epidemics can be traced back to the obvious source of external infection, each epidemic in the same year from June to July, the peak is mostly in September, December epidemic termination, never across the years. In view of this disease there is no reliable method of rapid diagnosis, it is necessary to strengthen the epidemic monitoring work, vigilance of the reintroduction of this disease. Since the first epidemic of dengue fever after liberation in Foshan City, Guangdong Province in 1978, the urban area of Guangzhou was also affected in that year. Cases of sporadic outbreaks and local small-scale outbreaks occurred. In 1980, a dengue epidemic occurred in Hainan Island and the epidemic spread to Guangzhou one after another in the same year. Until 1986, there have been four popular. The incidence of dengue in our city now report the following.