论文部分内容阅读
目的:探讨宫颈癌诊断中,血清肿瘤标志物鳞状上皮癌相关抗原(SCCA)、糖类抗原125(CA125)、糖类抗原15-3(CA15-3)和糖类抗原19-9(CA19-9)联合检测的应用价值。方法:选取我院宫颈癌、宫颈良性病变患者及健康人群各24例,以酶联免疫法测定SCCA,电化学发光法测定CA125、CA15-3和CA19-9。结果:宫颈癌组SCCA、CA125、CA15-3和CA19-9均显著高于良性组与健康对照组(P<0.05);SCCA、CA125、CA15-3和CA19-9联合测定具有较高灵敏度。结论:在宫颈癌诊断中,SCCA、CA125、CA15-3和CA19-9联合测定有利于诊断灵敏度的提升,故具有较高应用价值。
Objective: To investigate the diagnostic value of serum tumor markers squamous cell carcinoma associated antigen (SCCA), carbohydrate antigen 125 (CA125), carbohydrate antigen 15-3 (CA15-3) and carbohydrate antigen 19-9 (CA19 -9) the value of joint detection. Methods: Twenty-four patients with cervical cancer, benign cervical lesions and healthy subjects were enrolled in this study. SCCA was determined by enzyme-linked immunosorbent assay and CA125, CA15-3 and CA19-9 were determined by electrochemiluminescence. Results: The SCCA, CA125, CA15-3 and CA19-9 in cervical cancer group were significantly higher than those in benign group and healthy control group (P <0.05). The combination of SCCA, CA125, CA15-3 and CA19-9 had higher sensitivity. Conclusion: In the diagnosis of cervical cancer, SCCA, CA125, CA15-3 and CA19-9 joint determination is conducive to the improvement of diagnostic sensitivity, it has high value.