A Peptide Nucleic Acid to Reduce Type I Collagen Production by Fibroblast Cells

来源 :药物化学期刊(英文) | 被引量 : 0次 | 上传用户：emeng

【摘要】

：

In this study, we prepared a peptide nucleic acid (PNA) against the gene coding for the human alpha 1 chain of type I collagen. This PNA was incorporated into n

【作者】

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Yasutada Imamura Suzuka Tsuboi

【机构】

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DepartmentofAppliedChemistry,DepartmentofLifeSciences,FacultyofPharmaceuticalSciences

【出处】

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药物化学期刊(英文)

【发表日期】

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2015年1期

【关键词】

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COLLAGEN PNA ANTIGENE FIBROSIS VIMENTIN Collagen PNA Antigene Fibrosis Vimentin

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In this study, we prepared a peptide nucleic acid (PNA) against the gene coding for the human alpha 1 chain of type I collagen. This PNA was incorporated into normal human fibroblast cells by electroporation, leading to a decrease in the mRNA level of the

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A Peptide Nucleic Acid to Reduce Type I Collagen Production by Fibroblast Cells

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