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作者在前一个实验工作的基础上进一步扩大样本，对６７０名４岁以下儿童进行了为期二年的补充大剂量ＶＡ的实验观察，用双盲法对实验组儿童每６个月补充２０×１０４ＩＵＶＡ，由乡村医生每周访问儿童家长，记录儿童患病情况。结果表明对亚临床ＶＡ缺乏地区儿童补充大剂量ＶＡ能降低腹泻发生率，且其效果在疾病高发月份更明显，结果还表明血清ＶＡ低的儿童补充ＶＡ比血清ＶＡ水平较高的儿童效果明显；但对呼吸道感染性疾病虽然在疾病高发月份实验组发病比对照组低，但总的差异不明显。作者还对疾病资料收集方法进行了讨论。
Based on the previous experimental work, the authors further expanded the sample to conduct a two-year trial of 670 children under 4 years of high-dose VA. The double-blind method was used to supplement the experimental group with 20 × 104 IUVA every 6 months , Weekly visits by village doctors to parents of children record the child’s illness. The results showed that supplementation of children with subclinical VA deficiency in large doses of VA can reduce the incidence of diarrhea, and the effect of the disease is more obvious in the month of onset, the results also showed that children with low serum VA supplementation of VA VA than children with high serum VA significantly; However, although the incidence of respiratory tract infection in the experimental group in the high incidence of disease was lower than that in the control group, the overall difference was not obvious. The author also discussed disease data collection methods.