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Purpose To summarize the clinical profile and response to treatment of 4 biops y-proven cases of inflammatory orbital pseudotumor extending beyond the orbit. Design Retrospective observational case series. Methods Four patients’charts we re retrospectively reviewed. There were three men with extraorbital extension (t wo intracranial; one maxillary antrum) and one woman with intracranial disease t hat extended into the orbit. The men were 40, 41, and 60 years old; the woman wa s 73 years old. Results Two men with orbital myositis and mild discom fort, init ially treated with corticosteroids, had asymptomatic intracranial disease 9 and 12 months after initial presentation. A third man had extension into the maxilla ry antrumafter initial symptoms of painless diplopia. The woman had intraorbital disease with minimal discomfort (dacryoadenitis and myositis) 5 years after pre senting with intracranial disease in the Meckel cave that subsequently became bi lateral. Histopathologic examination in all cases showed nonspecific inflammatio n without evidence of vasculitis or granulomas. Conclusions Unlike typical cases of nonspecific orbital inflammation, two of these four cases did not have pain as a prominent feature. Neuroimaging was essential in diagnosing asymptomatic ex traorbital disease. Surgery has a prominent role in confirming this diagnosis, p rimarily by helping to rule out other diseases, such as those with granulomatous inflammation or vasculitis. Additional therapy was usually not required postope ratively.
Purpose To summarize the clinical profile and response to treatment of 4 biops y-proven cases of inflammatory orbital pseudotumor extending beyond the orbit. Design Retrospective observational case series. Methods Four patients’charts we retr retrometrically. There were three men with extraorbital extension ( the woman was 40 years old, the woman was 73 years old. Results Two men with orbital myositis and mild discom fort, init ially treated with corticosteroids, had asymptomatic intracranial disease 9 and 12 months after initial presentation. A third man had extension into the maxilla ry antrumafter initial symptoms of painless diplopia. The woman had intraorbital disease with minimal discomfort (dacryoadenitis and myositis) 5 years after pre senting with intracranial disease in the Meckel cave that next became bi lateral. Histopathologic examinat ion in all cases showed nonspecific inflammatio n without evidence of orascitalitis, two of these cases did not have pain as a prominent feature. Neuroimaging was essential in diagnosed asymptomatic ex trabbital disease. a prominent role in confirming this diagnosis, p rimarily by helping to rule out other diseases, such as those with granulomatous inflammation or vasculitis. Additional therapy was usually not required postope ratively.