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目的探讨联合超声检查及肿瘤标记物检测对卵巢肿瘤的诊断意义。方法选取2012年1月~2013年10月该院收治的具有完整临床资料,且经病理学检查明确诊断为卵巢肿瘤的患者49例。根据病理学检查结果分为卵巢良性肿瘤23例(良性组)及卵巢恶性肿瘤26例(恶性组),并对患者的临床资料进行回顾性分析,对比两组超声检查〔阻力指数(RI)、搏动指数(PI)〕及肿瘤标记物检测癌抗原(CA)199、CA125、癌胚抗原(CEA)结果,总结联合两种检查对卵巢肿瘤的诊断价值。结果恶性组RI、PI阳性率明显高于良性组,差异均有统计学意义(P<0.05)。恶性组CA199、CA125及CEA含量明显高于良性组,差异均有统计学意义(P<0.05)。超声检查、肿瘤标记物检测及联合两种检查对卵巢肿瘤均存在诊断意义,且联合两种检查的诊断率更高,差异有统计学意义(P<0.05)。结论联合超声检查及肿瘤标记物检测可显著提高对卵巢肿瘤的诊断意义。
Objective To investigate the diagnostic value of combined ultrasonography and tumor marker detection in ovarian tumors. Methods Forty-nine patients with complete clinical data who were diagnosed as ovarian tumors by pathology were selected from January 2012 to October 2013 in our hospital. According to the results of pathological examination, 23 cases of benign ovarian tumor (benign group) and 26 cases of malignant ovarian tumor (malignant group) were divided into two groups. The clinical data of the patients were retrospectively analyzed. Pulsatile index (PI)] and tumor markers detection of cancer antigen (CA) 199, CA125, carcinoembryonic antigen (CEA) results, summarize the combined diagnosis of two kinds of ovarian cancer diagnosis. Results The positive rate of RI and PI in malignant group was significantly higher than that in benign group, the difference was statistically significant (P <0.05). The levels of CA199, CA125 and CEA in malignant group were significantly higher than those in benign group (P <0.05). Ultrasound examination, tumor marker detection and the combination of the two tests have diagnostic significance for ovarian neoplasms, and the combined diagnosis of the two examinations is higher, the difference was statistically significant (P <0.05). Conclusion Combined ultrasound and tumor marker detection can significantly improve the diagnostic significance of ovarian tumors.