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讨论了口服控释小丸剂剂量的计算方法,以保证口服后在体内产生理想的血药浓度。也涉及工艺方法、包衣操作以及体内-体外相关性等问题。
The calculation method of oral controlled release pellet dosage is discussed to ensure the ideal blood concentration in the body after oral administration. There are also issues such as process methods, coating operations, and in vivo-in vitro relevance.