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目的比较氟桂利嗪与尼莫地平治疗偏头痛临床疗效。方法选择84例偏头疼患者,随机分为观察组(44例)与对照组(40例)。观察组给予每天口服氟桂利嗪胶囊10mg,对照组给予尼莫地平片一天3次,每次30mg,比较两组患者治疗效果。结果观察组治疗总有效率达90.91%,远高于对照组67.50%(P<0.05);观察组患者治疗后头痛发作持续时间、发作次数均明显短于对照组(P<0.05),患者头痛强度构成以轻度为主,明显好于对照组(P<0.05)。结论尼莫地平片和盐酸氟桂利嗪胶囊均能预防与治疗偏头痛,但氟桂利嗪效果更佳。
Objective To compare the clinical efficacy of flunarizine and nimodipine in the treatment of migraine. Methods Eighty-four patients with migraine were randomly divided into observation group (44 cases) and control group (40 cases). The observation group was given oral flunarizine capsule 10mg daily, while the control group was given nimodipine 3 times a day, each time 30mg. The treatment effect was compared between the two groups. Results The total effective rate of observation group was 90.91%, much higher than that of control group (67.50%, P <0.05). The duration of headache attack and the number of attacks in observation group were significantly shorter than those in control group (P <0.05) The intensity was mainly mild, which was significantly better than that of the control group (P <0.05). Conclusion Both nimodipine and flunarizine hydrochloride capsules can prevent and treat migraine headaches, but flunarizine is more effective.