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目的评价骨巨细胞瘤的临床、Ｘ线、病理学表现及三者结合综合分期的意义。方法收集经手术病理证实的骨巨细胞瘤７８例，以其临床、Ｘ线、病理特征为依据，进行临床分症，Ｘ线分型、病理分级三结合回顾性观察分析，将骨巨细胞瘤综合分为三期。结果三项均符合者６４例，占８２．０％。对Ⅰ、部分Ⅱ期的治疗选择瘤体刮除烧灼加植骨，部分Ⅱ期采用瘤体整块切除加植骨治疗共５６例，随访５年４例复发。对Ⅲ期患者采取截肢或瘤体整块切除加骨水泥充填，５年生存率５０．０％（６／６）。结论骨巨细胞瘤的三结合综合分期法对选择适当的治疗方案有重要的临床指导意义。
Objective To evaluate the clinical, X-ray and pathological features of giant cell tumor of bone and the significance of the combined staging of the three. Methods 78 cases of giant cell tumor of bone confirmed by operation and pathology were collected. Clinical, X-ray and pathological characteristics were used as the basis for clinical sub-clinical disease. X-ray classification and pathological grading were combined with retrospective observation and analysis. The giant cell tumor of bone was retrospectively analyzed. It is divided into three phases. Results There were 64 cases (82.0%) in all three items. The treatment of stage I and part II patients was performed with curative excision of the tumor and bone graft. In part II, 56 patients underwent whole tumor resection and bone grafting. Four patients were followed up for 5 years and relapsed. For patients with stage III amputation or tumor removal with bone cement filling, the 5-year survival rate was 50.0% (6/6). Conclusion The three-phase combined staging method for giant cell tumor of bone has important clinical guiding significance for selecting the appropriate treatment plan.