Targeted genotyping for the prediction of celiac disease autoimmunity development in patients with t

• 作 者: Maureen M Leonard Stephanie Ca
• 机 构: MucosalImmunologyandBiologyResearchCenter,CenterforCeliacResearchandTreatment,DepartmentofPediatricG
• 出 处: 世界糖尿病杂志:英文版(电子版)
• 发表日期: 2019年3期
• 关键词: Screening GLUTEN Diabetic COELIAC HAPTOGLOBIN Human LEUKOCYTE antigen
• 基金项目: The Center for Celiac Research and Treatment, The Nutrition Obesity Research Center at Harvard, No. P30-DK04561,to MML and RAB and The Harvard Clinical and Translational Science Center, the Harvard Ca

BACKGROUND Patients with type 1 diabetes (T1D) and their first-degree relatives (FDRs) have an increased risk of developing celiac disease (CD) compared to the general population. This is largely explained by the shared association with major histocompati