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通过7例白细胞减少症和7例对照组的精神分裂症患者,口服碳酸锂每日0.8g 4周内,外周血象中白细胞和粒细胞数变化的观察,发现14例患者服锂后白、粒细胞数均有增高,停锂后逐渐下降。特别在白细胞减少症组中具有统计学意义。所有患者未发生不良反应,血浆锂浓度在安全范围。证实碳酸锂是治疗白细胞减少症的安全有效药物,建议临床推广使用和进一步研究。
Through 7 cases of leucopenia and 7 cases of control group schizophrenic patients, orally administered lithium carbonate 0.8g per day for 4 weeks, the peripheral blood leukocytes and granulocytes in the number of changes observed in 14 patients with lithium service white, grain The number of cells were increased, gradually decreased after stopping lithium. Especially in leukopenia group was statistically significant. All patients had no adverse reactions, plasma lithium concentration in the safe range. Confirmed that lithium carbonate is a safe and effective treatment of leukopenia drugs, it is recommended for clinical use and further study.