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目的了解安徽省成年人群血脂异常特征。方法以多阶段分层整群随机抽样方法,抽样安徽省24个乡镇(街道),72个村(居委会)地区3 600户居民,每户随机抽样调查18岁以上居民1人。采用问卷调查和医学体检,对每一名被调查者进行身高、体重、血压等测量,并采集空腹及餐后2h静脉血进行血糖、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)检测。结果成年人群血脂TC、TG、HDL-C、LDL-C异常患病率分别为:4.0%、11.6%、27.4%、1.9%。男性TG、HDL-C异常患病率(13.8%、31.4%)高于女性(9.9%、24.2%)(P<0.01,OR值分别为1.458、1.447)。18~59岁年龄段人群血脂TG、HDL-C异常患病率呈上升趋势。BMI≥24.0 kg/m2、高血压、糖尿病人群中合并高TG血症者分别占18.5%、15.7%、21.1%,人群高TG血症与超重、高血压、糖尿病相关OR值分别达到3.247、2.029、2.438。结论安徽省成年人群血脂异常以高TG血症、低HDL-C血症为主要特点,人群高TG血症与超重、高血压、糖尿病相关。应引导大众科学健康饮食、控制体重、健康生活方式,以有效控制人群血脂异常的流行。
Objective To understand the characteristics of dyslipidemia in adults in Anhui Province. Methods A multistage stratified cluster random sampling method was used to sample 3 600 households from 24 townships (neighborhoods) and 72 villages (neighborhood committees) in Anhui Province. Each household sampled 1 resident above 18 years old randomly. Using questionnaire and medical examinations, the height, weight, blood pressure and other measurements of each respondent were collected. Fasting and postprandial venous blood samples were collected for blood glucose, total cholesterol (TC), triglyceride (TG), low density Lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) detection. Results The prevalence of abnormal TC, TG, HDL-C and LDL-C in adults was 4.0%, 11.6%, 27.4% and 1.9%, respectively. The abnormal prevalence of TG and HDL-C in males was 13.8% and 31.4% higher than that in females (9.9% and 24.2% respectively) (P <0.01, OR = 1.458 and 1.447, respectively). The prevalence of abnormal TG and HDL-C in 18 ~ 59 age group is on the rise. BMI≥24.0 kg / m2, hypertension and diabetic patients with hypertriglyceridemia accounted for 18.5%, 15.7% and 21.1%, respectively. The OR of high triglyceride, overweight, hypertension and diabetes were 3.247 and 2.029 , 2.438. Conclusion The prevalence of dyslipidemia in adult population in Anhui Province is characterized by hypercholesteremia and hypo HDL-C. The prevalence of hypercholesteremia is related to overweight, hypertension and diabetes. Should guide the public scientific and healthy diet, weight control, healthy lifestyle, in order to effectively control the crowd’s prevalence of dyslipidemia.