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为了提高精制原代地鼠肾细胞狂犬病疫苗 (PPHKRV)的质量 ,在甲醛浓度 ,温度和时间相同的条件下 ,对静置法和转瓶法灭活狂犬病毒后制成的疫苗进行了效力测定比较 ,结果表明采用转瓶灭活的PPHKRV效力高于静置灭活法。
In order to improve the quality of refined primary murine renal cell rabies vaccine (PPHKRV), the efficacy of the vaccines prepared by the static method and the bottle-shaker inactivation of rabies virus was tested under the same formaldehyde concentration, temperature and time The results showed that PPHKRV inactivated by spinner flask was more effective than static inactivation method.