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本文作者认为人工血应具备以下基本条件,(1)必须有充分的携氧能力并能释放给周围组织利用,(2)促使氧气迅速可逆地结合和释放。(3)在血流中有一定的停留时间,(4)完成运转氧气的功能之后迅速从机体排泄。(5)对机体任何器官不应产生任何功能性或病理性变化。根据这些作者与日本绿十字会联合生产出以7份全氟萘烷和3份全氟三丙胺为主要成份的人工血称Fluorosal DA(20%),并加F_(68)乳化剂和HES电解质等供临床应用。该乳剂颗粒稳定,毒性低,大量动物试验和临
The authors believe that artificial blood should have the following basic conditions, (1) must have sufficient oxygen carrying capacity and can be released to the surrounding tissue utilization, (2) to promote rapid and reversible oxygen binding and release. (3) There is a certain dwell time in the bloodstream, (4) Excretion of body oxygen quickly after completing the function of running oxygen. (5) No functional or pathological changes should be made to any organ of the body. According to these authors, the artificial blood called Fluorosal DA (20%) containing 7 parts of perfluorodecalin and 3 parts of perfluorotripropanolamine was produced jointly with the Green Cross of Japan and F_ (68) emulsifier and HES electrolyte For clinical application. The emulsion particles are stable, low toxicity, a large number of animal experiments and temporary