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目的：回顾分析了法国巴黎Ｔｅｎｏｎ医院放疗科１９７６年２月～１９９３年１月收治的４９例脑膜瘤患考的放疗经验。材料与方法：Ａ组１５例采用完全切除术后放疗，Ｂ组１０例次全切除术后放疗；Ｃ组７例系术后复发放疗；Ｄ组为单纯放疗１７例。结果：各组１、２，３年生存率分别为，Ａ组１００％％；８０％和６６．７％：Ｂ组９０％，７５．５％和６６．７％：Ｃ组８５．７％，８３．３％和８０％：Ｄ组９４．１％，６８．８％和７２．７％。各组放疗后临床症状好转率：Ａ组６６．７％，Ｂ组５０％，Ｃ组７１．７％；Ｄ组３５．３％。１例放疗后３年发生闭经：１例左眼失明；３例死于远处转移；２例死于局部发展；７例死于其他原因。结果显示放疗在完全切除术后对临床症状改善和生存的影响无明显优于其他组的作用。结论：脑膜瘤次全切除术后应予以放疗；术后复发或手术困难的原发脑膜瘤可以行根治性放疗。各组无１例脑坏死发生。
OBJECTIVE: To retrospect the radiotherapy experience of 49 patients with meningioma admitted to the Department of Radiation Oncology, Tenon Hospital, Paris, France from February 1976 to January 1993. Materials and Methods: A group of 15 cases with complete resection of radiotherapy, B group of 10 cases of subtotal radiotherapy; C group of 7 cases of postoperative recurrence and radiotherapy; D group was radiotherapy alone in 17 cases. Results: The 1, 2, 3-year survival rates in each group were 100 %% in group A, 80% and 66.7% in group A, 90%, 75.5% and 66.7% in group B, 85.7% , 83.3% and 80% respectively: 94.1%, 68.8% and 72.7% in group D. The improvement rate of clinical symptoms after radiotherapy in each group was 66.7% in group A, 50% in group B, 71.7% in group C and 35.3% in group D, respectively. A case of amenorrhea occurred 3 years after radiotherapy: 1 case of left eye blindness; 3 died of distant metastases; 2 died of local development; and 7 died of other causes. The results showed that the effect of radiotherapy on clinical symptom improvement and survival after complete resection was not significantly better than that of other groups. Conclusion: Subtotal meningioma should be treated with radiotherapy. The primary recurrent or difficult primary meningiomas can be treated by radical radiotherapy. No brain necrosis occurred in each group.