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目的:探讨血瘀证与冠状动脉狭窄以及冠脉介入术后再狭窄的相关性。方法:随访408例进行介入治疗的冠心病患者,在介入治疗前1天、介入治疗后1月、6月观察中医证型等,并与介入时的冠脉病变特征进行对比分析。结果:(1)血瘀证患者低密度蛋白水平明显高于非血瘀证患者;(2)介入治疗前血瘀证257例(62.9%),其中心血瘀阻证131例(32.1%),气虚血瘀证126例(30.8%);介入治疗6月后,血瘀证243例(59.6%),其中心血瘀阻证86例(21.1%),气虚血瘀证157例(38.5%),介入治疗后血瘀虚证显著增多;(3)血瘀证患者中冠状动脉狭窄程度重、病变节段数多,以血瘀实证最为严重;(4)再狭窄在血瘀证中最容易发生,其中在心血瘀阻证最为显著。结论:血瘀证与冠状动脉病变严重程度、冠状动脉介入治疗后再狭窄存在相关性。
Objective: To investigate the relationship between blood stasis syndrome and coronary artery stenosis and restenosis after coronary intervention. Methods: A total of 408 patients with coronary heart disease who underwent interventional therapy were followed up. One day before interventional treatment and one month and 6 months after interventional therapy, TCM syndromes were observed and compared with those of coronary artery disease during intervention. Results: (1) Low density protein in patients with blood stasis syndrome was significantly higher than those in non-blood stasis syndrome patients. (2) 257 cases (62.9%) had blood stasis syndrome before intervention, 131 cases (32.1%) had blood stasis syndrome, 126 cases (30.8%) of Qi deficiency and blood stasis syndrome, 243 cases (59.6%) of blood stasis syndrome, 86 cases (21.1%) of central blood stasis syndrome and 157 cases (38.5% Blood stasis syndrome after interventional therapy significantly increased; (3) blood stasis in patients with severe coronary stenosis, lesion number more to the most serious evidence of blood stasis; (4) restenosis is most likely to occur in the blood stasis, Among them, the most obvious is blood stasis syndrome. Conclusion: There is a correlation between the blood stasis syndrome and the severity of coronary artery disease and the restenosis after coronary intervention.