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目的了解医务人员鼻腔携带表皮葡萄球菌耐药情况及是否存在其流行株。方法对我院医务人员鼻腔表葡菌携带调查。结果发现其携带率为61.95%,儿科、神经外科工作人员携带率分别为88.89%、89.47%,经质粒及质粒限制性内切酶分析证实:极大部分工作人员鼻腔携带菌质粒图谱各异,而小儿科、神经外科有少数菌株质粒酶切图谱相同,说明可能存在交叉感染。结论本组菌株β-内酰胺酶阳性率为85.93%,MRSE检出率为75.00%,此与医务人员长期接触β-内酰胺类抗生素有关;本组菌株粘质阳性率为23.43%,说明医务人员携带以正常菌为多,侵袭菌株少
Objective To understand the medical staff carrying nasal Staphylococcus epidermidis resistance and the existence of its epidemic strains. Methods of medical staff in our hospital nasopharyngeal Staphylococcus aureus carrying investigation. The results showed that the carrying rate was 61.95%, pediatric, neurosurgery staff carrying rates were 88.89%, 89.47%, plasmid and plasmid restriction endonuclease analysis confirmed: a large part of the staff carrying the nose Mycoplasma plasmid map different, and pediatrics, neurosurgery a few strains of plasmid digestion map the same, indicating the possibility of cross-infection. Conclusion This group of strains β-lactamase positive rate was 85.93%, MRSE detection rate was 75.00%, which was linked to long-term medical staff β-lactam antibiotics; sticky positive rate of this group of strains 23 .43%, indicating that medical staff to carry more normal bacteria, less invasive strains