论文部分内容阅读
金黄色葡萄球菌肠毒素(SE)是一种外源性超级抗原,仅需微量即能能刺激非特性T细胞的大量增殖,促使产生大量和多种细胞因子及细胞毒,提高机体免疫力,使之获得抗肿瘤的能力,故是一种很有前途的新型肿瘤免疫治疗剂,目前已开始已用于肿瘤患者的辅助治疗。本文对葡萄球菌肠毒素的结构、抗肿瘤作用机理及其应用前景作了简要综述。
Staphylococcus aureus enterotoxin (SE) is an exogenous superantigen that requires only a trace amount of stimulation of non-specific T cells in large quantities to promote the production of a large number and a variety of cytokines and cytotoxicity, improve immunity, So that the ability to obtain anti-tumor, it is a promising new tumor immunotherapeutic agents, has now begun to be used for adjuvant treatment of cancer patients. In this paper, the staphylococcal enterotoxin structure, anti-tumor mechanism and its application prospects are briefly reviewed.