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华中五味子(Schisandra sphenanthera)是一种中国的药用植物。它的果实经空气干燥粉碎后依次用石油醚、乙醚、甲醚提取,其乙醚提取物经硅胶(20～30μ)柱(3×60cm)层折,依次用石油醚、石油醚—10％丙酮、石油醚—20％丙酮、石油醚—40％丙酮洗脱,分别得到部分P_1、P_2、P_3、P_4。P_2部分再经硅胶(40μ)柱(1.5×25cm)层析,用逐渐增加乙酸乙酯含量(15～50％)的石油醚洗脱,得出粗品ganschisandrine(1),经正己烷—乙醚重结晶,得到白色片状结晶(1),C_(22)H_(25)O_5mp114～115℃,〔a〕~D_(20)+173.1~o(C.0.26,氯
Schisandra sphenanthera is a Chinese medicinal plant. Its fruit was air-dried and crushed and then extracted with petroleum ether, ether and methyl ether in turn. The ether extract was layer-folded on a column of silica gel (20-30 μm) (3×60 cm), followed by petroleum ether, petroleum ether and 10% acetone. , petroleum ether - 20% acetone, petroleum ether - 40% acetone elution, respectively, part of P_1, P_2, P_3, P_4. The P_2 fraction was further chromatographed on a silica gel (40μ) column (1.5×25cm) and eluted with increasing amounts of ethyl acetate (15-50%) in petroleum ether to give the crude ganschisandrine (1), which was resuspended with n-hexane-ether. Crystallization gave white flaky crystals (1), C_(22)H_(25)O_5mp 114~115°C, [a]~D_(20)+173.1~o(C.0.26, chlorine