论文部分内容阅读
现对几种常用的抗心律失常的药物作一介绍:一、奎尼丁1.作用:能延长心肌不应期;降低应激性与传导性;抑制正常及异位冲动的形成;对周围血管有阻滞α受体作用,使血管扩张,血压在下降。2.副作用:过敏反应有发热皮肤红斑,血管神经性水肿,呼吸困难,晕厥等。过量反应有恶心,呕吐、腹痛、腹泻、头痛、头昏、耳聋、视力障碍等(奎尼反应)、心率加快、血压降低;心电图变化QRS 增宽 PR 间期及 QT 间期延长,U 波出现、室性早搏、阵发性室速、室颤。3.适应症:频发房早、房速、房扑、房颤等。
Now several commonly used anti-arrhythmic drugs make a presentation: First, quinidine 1. Role: to extend myocardial refractory period; reduce stress and conductivity; inhibit normal and ectopic impulse formation; around the Blood vessels block the role of α receptor, the blood vessels to dilate, blood pressure is declining. 2 side effects: allergic reactions have fever, skin erythema, angioedema, dyspnea, fainting and so on. Excessive reactions were nausea, vomiting, abdominal pain, diarrhea, headache, dizziness, deafness, visual impairment, etc. (Quinini reaction), heart rate increased, blood pressure decreased; ECG changes QRS widening PR interval and QT interval prolonged U wave , Premature ventricular contractions, paroxysmal ventricular tachycardia, ventricular fibrillation. Indications: frequent room early, atrial tachycardia, atrial flutter, atrial fibrillation and so on.