论文部分内容阅读
将７９例诊断明确的不同病因引起的腹水分为结核、非结核良性及恶性腹水３组。同步检测腹水糖抗原５０（ＣＡ５０）、癌胚抗原（ＣＥＡ），结果恶性腹水ＣＡ５０和ＣＥＡ明显高于结核性及非结核良性腹水，Ｐ＜０．０１。ＣＡ５０诊断恶性腹水的敏感性和特异性分别为７７．８％和９３％，ＣＥＡ的敏感性和特异性分别为５２．８％和９３％，二者联合检测的敏感性为８９．６％、特异性为８６．５％。本文提示：ＣＡ５０、ＣＥＡ对良恶性腹水有鉴别价值，且不受结核等渗出性腹水的影响。作为单项标记，ＣＡ５０诊断恶性腹水的敏感性优于ＣＥＡ，联合检测可使诊断恶性腹水的敏感性明显增高，因而有互补作用。
Eighty-nine cases diagnosed with different etiologies had abdominal fluids of tuberculosis, non-tuberculous benign and malignant ascites. Simultaneous detection of ascites carbohydrate antigen 50 (CA50), carcinoembryonic antigen (CEA) results in malignant ascites CA50 and CEA were significantly higher than tuberculous and non-tuberculous benign ascites, P<0.01. The sensitivity and specificity of CA50 in diagnosing malignant ascites were 77.8% and 93%, respectively. The sensitivity and specificity of CEA were 52.8% and 93%, respectively. The combined sensitivity of CA50 was 89.6%. The specificity is 86.5%. This article suggests that: CA50, CEA differential diagnosis of benign and malignant ascites, and is not affected by tuberculosis and other ascites. As a single marker, the sensitivity of CA50 in the diagnosis of malignant ascites is better than that of CEA. Joint detection can make the diagnosis of malignant ascites more sensitive, and thus has a complementary effect.