大鼠体内热休克蛋白的表达与抗弓形虫保护性免疫间的关系

• 作 者: 张述义
• 出 处: 国外医学(寄生虫病分册)
• 发表日期: 1994年05期
• 关键词: 保护性免疫 弓形虫感染 大鼠 巨噬细胞 速殖子 免疫印渍技术 小鼠腹腔 致死量 缓殖子 毒力

作者曾报告宿主巨噬细胞上热休克蛋白65(HSP65)的表达与感染弓形虫小鼠获得保护性免疫有明显关系。为了弄清这种关系是否与宿主种类有关,又用大鼠进行了一些实验。所用动物为雌性BALB/c(H—2~d)小鼠;

The authors have reported a significant relationship between the expression of heat shock protein 65 (HSP65) on host macrophages and the protective immunity in mice infected with Toxoplasma gondii. In order to find out if this relationship is related to the host species, some experiments were performed in rats. Animals used were female BALB / c (H-2 ~ d) mice;