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本文对1989年9月至1995年2月收治的112例小儿特发性血小板减少性紫癜的血小板相关性抗体、T细胞亚群检测及其临床意义进行了探讨。结果表明:急、慢型无论是OKT3及OKT4+均低于正常对照组,且有显著性差异,P值均<0.05;而OKT8+与正常对照组相比则较高,P值<0.025。但是,急、慢两型相比均未见统计学上显差性差异。本文的检测血小板抗体lgG、IgM及IgA,显示均有所增高尤以PAIgG最明显,阳性率达85.7%,与文献报道近似。经治疗10例血小板动态变化,PAIg随着血小板的恢复均下降至正常,呈负相关.
This article from September 1989 to February 1995 admitted 112 cases of idiopathic thrombocytopenic purpura platelet-related antibodies, T cell subsets detection and its clinical significance were discussed. The results showed that both OKT3 and OKT4 + were lower than the normal control group, and there were significant differences between the two groups (P <0.05). OKT8 + was higher than the normal control group (P <0). 025. However, there is no statistically significant difference between acute and slow type. The detection of platelet antibodies lgG, IgM and IgA, all showed increased PAIgG especially the most obvious, the positive rate of 85.7%, and the literature reported similar. After the treatment of 10 cases of platelet dynamic changes, PAIg with platelet recovery decreased to normal, was negatively correlated.