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检测血清β-hCG各种手段的发展,明显促进了滋养层疾病的治疗与随访。但在一些病例,血清大量β-hCG可导致高水平的“倒钩效应(hook effect)”,造成血中低水平的假象,使对病人的治疗出现意想不到的问题。当这种病人的血清稀释后,则会发现其hCG水平实际很高。1985～1990年Beilinson医疗中心妇科肿瘤科共诊治93例完全性葡萄胎患者。其中2例出现大量β-hCG导致的高水平倒钩效应。
Detection of serum β-hCG various means of development, significantly promoted the treatment and follow-up of trophoblast disease. However, in some cases, high levels of beta-hCG in serum can lead to high levels of “hook effects,” creating low-level artifacts in the blood that present unexpected problems in the treatment of patients. When this patient’s serum is diluted, it is found that the hCG level is actually high. From 1985 to 1990, 93 cases of complete hydatidiform mole were diagnosed and treated by Beilinson Medical Center Gynecologic Oncology. Two of these patients developed high levels of barb-induced effects of β-hCG.