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目的分析武汉地区2009年至2013年抗结核药物的应用情况,为临床合理用药提供参考。方法对2009年至2013年武汉地区34家入网医院抗结核药物的用药金额、用药频度(DDDs)、日均费用(DDC)进行统计分析。结果武汉地区年抗结核用药金额及DDDs逐年增加,一线抗结核药物仍占主导地位,二线抗结核药物用量虽呈逐年增加趋势,但其比例仍小于一线抗结核药。经典抗结核药物DDDs仍居主导地位,新的抗结核药物也在逐渐扩大应用。结论武汉地区医院抗结核药物临床应用基本合理,也反映了目前结核病治疗的发展趋势,但中成药抗结核病的疗效仍有待评估。
Objective To analyze the application of anti-tuberculosis drugs in Wuhan from 2009 to 2013 and provide a reference for clinical rational drug use. Methods The amounts of anti-TB drugs, DDDs and DDC in 34 network-entry hospitals in Wuhan from 2009 to 2013 were analyzed statistically. Results The amount of anti-TB drugs and DDDs in Wuhan increased year by year. The number of first-line anti-TB drugs still dominates. However, the amount of second-line anti-TB drugs shows an increasing trend year by year, but its proportion is still smaller than that of first-line anti-TB drugs. DDDs, the classic antituberculosis drugs, still dominate, and new antituberculosis drugs are gradually expanding their use. Conclusion The clinical application of antituberculosis drugs in hospitals in Wuhan area is basically reasonable and reflects the current trend of tuberculosis treatment. However, the curative effect of proprietary Chinese medicines against tuberculosis remains to be evaluated.