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1983年10月16～18日宁夏科委、宁夏卫生厅、山东省医药管理局、宁夏医药管理局在银川市主持召开了从苦豆子中提取分离苦参碱及其制剂妇炎栓鉴定会。宁夏盐池制药厂以苦豆子Sophora alepecuroides L.为原料提取分离得到苦参碱,药理试验证明有抑菌、抗炎作用。山东省海洋药物科学研究所将其制成制剂妇炎栓,对310例慢性宫颈炎患者进行了临床疗效观察。结果表明,疗效较好(治愈显效率为70.33%,总有效率91.62%),未见明显毒副作用。其中40例患者3年后追访,证明远期疗效较为满意。另对60例患者进行了双盲法试验,其结果妇炎栓组与空白对照组有显著差异。与会代表经过认真评议一致认为:(1)苦豆子资源丰富,从中提取药用苦参碱工艺合理,产品得率和纯度
From October 16 to 18, 1983, the Ningxia Science and Technology Commission, the Ningxia Health Department, the Shandong Provincial Pharmaceutical Administration, and the Ningxia Pharmaceutical Administration presided over the identification meeting for the extraction and separation of matrine and its preparation Fuyan Suppositories from Sophora alopecuroides. Ningxia Yanchi Pharmaceutical Factory extracted and isolated matrine by using Sophora alepecuroides L. as a raw material, and pharmacological tests proved that it has antibacterial and anti-inflammatory effects. Shandong Province Institute of Marine Drugs made its preparation Fuyan Suppository and observed the clinical curative effect of 310 patients with chronic cervicitis. The results showed that the curative effect was better (the cured effective rate was 70.33%, the total effective rate was 91.62%), and no obvious toxic and side effects were observed. Among them, 40 patients were followed up after 3 years, which proved that the long-term efficacy was satisfactory. A double-blind test was performed on 60 patients. The results showed significant differences between the Fuyan suppository and the control group. After a serious review, the participants agreed that: (1) The bitter beans are rich in resources, and the process of extracting medicinal matrine from them is reasonable, and the product yield and purity