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为了明确激素替代治疗(HRT)用于有症状的早期乳腺癌妇女的临床可行性,英国两家医院随机研究门诊100例参加实验的妇女,她们患有早期(1～2期)乳腺癌,并有雌激素缺乏引起的血管症状和阴道干燥。在参加实验的6个月内,选择应用或不应用HRT,主要观察指标是接受治疗的人数,持久治疗率。 结果 38.8％(100/261)的妇女接受实验,共100例,其中51例不曾服用三苯氧胺,49例曾服用三苯氧胺。持久治疗率为80％,75％的妇女在临床实验结束后,继续使用
To clarify the clinical feasibility of hormone replacement therapy (HRT) for women with symptomatic early breast cancer, two hospitals in the UK randomly studied 100 women who participated in the experiment. They had early (stage 1 to 2) breast cancer, and Vascular symptoms and vaginal dryness caused by estrogen deficiency. Within 6 months of participating in the experiment, HRT was selected or not applied. The main observations were the number of patients treated and the rate of long-lasting treatment. RESULTS: 38.8% (100/261) of the women underwent the test. A total of 100 patients were involved, of which 51 did not take tamoxifen and 49 had been treated with tamoxifen. The persistent treatment rate is 80%, 75% of women continue to use after the end of clinical trials