肝脏疾病过程中的肾小球肾病

• 作 者: Nochy D 沈洁
• 出 处: 国外医学(内科学分册)
• 发表日期: 1980年04期
• 关键词: 肝脏疾病 肾小球肾炎 肾小球肾病 酒精性肝病 主要情况 免疫荧光法 感染因子 免疫复合体 肝硬化 肾小球

目前,已确定在肝脏病患者中有相当数量的病人有某种肾小球肾炎。根据免疫荧光法的最近研究可对这些肾小球肾炎进行很好的定性,可以简单地区分两种主要情况。一种情况是多年来所描述的酒精性肝病同时伴有肾小球肾炎,可以认为肾小球肾炎是肝脏疾病的后果。另一种情况是感染因子(病毒、寄生虫)引起肝脏疾病和由于循环免疫复合体沉积所引起的肾小球肾炎。在这种情况下,抗原是感染因子,肝脏疾病和肾小球疾病相互之间可能完全无关。

At present, it has been determined that a significant number of patients with liver disease have some type of glomerulonephritis. According to recent studies with immunofluorescence, these glomerulonephritis can be well characterized and the two main cases can be easily distinguished. One situation is that alcoholic liver disease, which has been described for many years, is accompanied by glomerulonephritis and can be considered as a consequence of liver disease. In another situation, infectious agents (viruses, parasites) cause liver disease and glomerulonephritis due to the deposition of circulating immune complexes. In this case, the antigen is the infectious agent, liver disease and glomerular disease may be completely unrelated to each other.