论文部分内容阅读
业已证明,缺血性心肌病缺血后再灌注时,可见心肌内氧自由基增多,其机制是①线粒体电子传递系统的氧自由基漏出;②缺血后白细胞和巨噬细胞活化,氧自由基产生增多;③由于儿茶酚胺的作用,氧自由基生成增加;④缺血时次黄嘌呤、黄嘌呤氧化酶产生,再灌注时则氧自由基生成增多;⑤花生四烯酸
It has been shown that ischemic cardiomyopathy after ischemia and reperfusion, showing increased intracellular oxygen free radicals, the mechanism is ① mitochondrial electron transport system of oxygen free radicals leak; ② ischemia after activation of white blood cells and macrophages, oxygen free Radical generation increased; ③ due to the role of catecholamines, oxygen free radicals increased; ④ hypoxanthine, xanthine oxidase produced when ischemia, oxygen radicals generated when reperfusion increased; ⑤ arachidonic acid