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母婴传播是乙型肝炎(下称乙肝)的主要传播方式之一。婴儿在围产期感染乙型肝炎病毒(HBV)后易成为慢性携带者,严重的发展为慢性肝炎,肝硬变和原发性肝细胞癌等。因此,阻断母婴传播,控制乙肝在婴幼儿中的流行,对保护儿童身体健康有着重要的意义。本文在调查乙肝母婴传播机率的基础上,比较观察用乙肝免疫球蛋白(H Blg)加乙肝疫苗和单用乙肝疫苗的两种免疫方法阻断母婴传播的效果。材料与方法
Mother-to-child transmission is one of the main modes of transmission of hepatitis B (hereinafter referred to as hepatitis B). Infants in the perinatal infection with hepatitis B virus (HBV) easily become a chronic carrier, severe development of chronic hepatitis, cirrhosis and primary hepatocellular carcinoma. Therefore, blocking mother-to-child transmission and controlling the prevalence of hepatitis B in infants and young children are of great significance for the protection of children’s health. On the basis of investigating the probability of mother-to-child transmission of hepatitis B, we compared the effects of two immunizations with hepatitis B immunoglobulin (HBeAg) plus hepatitis B vaccine and hepatitis B vaccine alone. Materials and Methods