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目的:通过研究颈动脉内-中膜厚度(carotid Intimal medial thickness cIMT)及踝肱指数(ankle-brachial index,ABI)与冠心病患者的相关性,探讨动脉硬化和动脉粥样硬化之间的相关性。方法:本研究入选264例在本院行冠脉造影的患者,按冠脉造影的结果分为对照组和冠心病组,冠心病组根据冠脉病变程度进一步分为单支、双支、多支病变组。所有入选者在冠脉造影前用日本ALOKAα7超声检测cIMT,用日本科林无创动脉硬化测定仪测量两侧ABI。结果:冠心病组cIMT明显高于对照组,踝臂指数明显低于对照组,差异有统计学意义(P<0.05);冠状动脉病变程度分析中:cIMT随着冠脉病变程度加重均有增高趋势,其中多支病变、双支病变组cIMT和颈动脉斑块积分均高于单支病变组、对照组,单支病变组cIMT和颈动脉斑块积分也明显高于对照组;ABI却随着冠脉病变程度加重均有降低趋势,多支病变组ABI均低于双支、单支病变组和对照组,双支、单支病变组ABI也明显低于对照组,差异有统计学意义(P<0.05)。结论:cIMT和ABI与冠心病密切相关,在一定程度上可以预测冠心病冠脉病变程度。
OBJECTIVE: To investigate the association between atherosclerosis and atherosclerosis by studying the association between carotid intimal medial thickness cIMT and ankle-brachial index (ABI) and coronary heart disease Sex. Methods: The study selected 264 patients undergoing coronary angiography in our hospital, according to the results of coronary angiography is divided into control group and coronary heart disease group, coronary heart disease group according to the extent of coronary artery disease is further divided into single, double, multi Branch disease group. All participants were examined for cIMT by Japanese ALOKAα7 before coronary angiography and ABI by bilateral noninvasive arteriosclerosis instrument. Results: The cIMT in coronary heart disease group was significantly higher than that in control group, and the ankle-brachial index was significantly lower than that in control group (P <0.05). In the degree of coronary artery disease, cIMT increased with the severity of coronary artery disease Trend, in which multi-vessel disease, double-vessel disease group cIMT and carotid plaque score were higher than single-vessel disease group, control group, single-vessel disease group cIMT and carotid plaque score was significantly higher than the control group; ABI with ABI of multi-vessel disease group was lower than that of double-vessel, single-vessel lesion group and control group, ABI of double vessel and single vessel lesion group was also lower than that of control group, the difference was statistically significant (P <0.05). Conclusion: cIMT and ABI are closely related to coronary heart disease, to a certain extent, coronary artery disease can predict coronary artery disease.