论文部分内容阅读
利福平(rifampicin)毒副反应时有报道,现将我院遇到由利福平引起急性肾功能衰竭2例报道如下。患者女,64a,1967年曾患过结核,用过异烟肼、链霉素。1989年3月10日因胸痛不适、自服利福平0.6g,tid,1wk后发热,T39℃,自行停用利福平,d2(第2天)症状缓解。3月20日中午再次服利福平0.6g,于下午2时左右再度出现畏寒、发热、T40℃,且伴腹泻、恶心呕吐。自服速效伤风胶囊2粒、黄连素0.4g,bid,当日下午排尿10mL左右,较浓稠,3月23日又出现全身酸痛,给于住院治疗。入院当天已无尿72h,查肾功能:BUN27.49 mmol/L,Cr433μmol/L。3月24日复查肾功能:BUN
Rifampicin (rifampicin) side effects have been reported, now our hospital encountered rifampicin caused by acute renal failure in 2 cases are reported below. Female patient, 64a, had tuberculosis in 1967, used isoniazid, streptomycin. March 10, 1989 due to chest pain, self-serving rifampicin 0.6g, tid, 1wk after fever, T39 ℃, self-disable rifampicin, d2 (2 days) symptoms ease. At noon on March 20 again taking rifampicin 0.6g, reappeared at about 2 pm chills, fever, T40 ℃, and with diarrhea, nausea and vomiting. Self serving self-made capsules 2 capsules, berberine 0.4g, bid, on the afternoon of urination around 10mL, more thick, March 23 and body aches appeared again for hospitalization. The day of admission had no urine 72h, check the renal function: BUN27.49 mmol / L, Cr433μmol / L. March 24 review of renal function: BUN