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本文采用ELISA方法,检测了130例各型肝病和80例HBsAg无症状携带者的血清e抗原抗体系统与聚合人血清白蛋白受体(PHSAR)关系,发现在85例HBeAg阳性病人中有79例PHSAR阳性占91%(79/85),表明二者有密切关系,呈正相关,也表明PHSAR可敏感的反映HBeAg的存在,并提示HBV的复制活跃,因此,PHSAR的检测比HBeAg较为敏感,更有助于临床诊断和预后判断,PHSAR转阴同时HBeAg也转阴,则说明预后良好,如产生抗-PHSAR抗体,可视为该病毒已被彻底清除。
In this study, ELISA method was used to detect the relationship between serum e antigen antibody system and polymeric human serum albumin receptor (PHSAR) in 130 cases of various liver diseases and 80 cases of HBsAg asymptomatic carriers. It was found that among 85 cases of HBeAg-positive patients, 79 cases PHSAR positive accounted for 91% (79/85), indicating that the two are closely related, is positively correlated, also shows that PHSAR can reflect the presence of HBeAg and prompt HBV replication active, therefore, PHSAR detection is more sensitive than HBeAg more Contribute to clinical diagnosis and prognosis, PHSAR negative at the same time HBeAg also negative, then the prognosis is good, such as anti -PHSAR antibody, can be considered as the virus has been completely removed.