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目的分析神经梅毒的临床特征。方法回顾分析我院30例神经梅毒患者的年龄、性别、临床表现、脑脊液改变和神经影像学检查等资料。结果30例患者符合神经梅毒的诊断。最常见的临床类型为脑膜血管型梅毒占37%,其次为脊髓痨占20%、麻痹性痴呆占20%。平均发病年龄是50.8岁,除了1例为女性外,均为男性。常见的症状是脑卒中,占37%,常见的体征是腱反射减弱、痴呆和深感觉障碍,分别占30%。结论神经梅毒的临床表现复杂多样,临床上应高度警惕。
Objective To analyze the clinical features of neurosyphilis. Methods Retrospective analysis of 30 patients with neurosyphilis in our hospital age, gender, clinical manifestations, cerebrospinal fluid changes and neuroimaging and other data. Results 30 patients with neurosyphilis diagnosis. The most common clinical types were meningeal vascular syphilis 37%, followed by spinal cord gallbladder 20%, paralytic dementia 20%. The average age of onset was 50.8 years, except for 1 case of female, both men. Common symptoms are stroke, accounting for 37% of the common signs of reduced tendon reflexes, dementia and deep sensory disturbances, respectively, 30%. Conclusion The clinical manifestations of neurosyphilis are complex and diverse and should be highly vigilant in clinical practice.