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以酶联免疫吸附法对85例脑梗塞患者(<50岁37例,≥50岁48例),21例非缺血性脑血管病患者及14名正常人的血清抗心肌磷脂抗体(aCL)进行测定,结果<50岁和≥50岁脑梗塞患者的aCL阳性率均明显高于对照组(均P<0.05);而<50岁脑梗塞患者的aCL阳性率明显高于≥50岁患者(P<0.05)。提示临床上无任何自身免疫疾病的中青年脑梗塞患者与aCL相关更为密切。
Serum anti-cardiolipin antibodies (aCL) in 85 patients with cerebral infarction (37 in <50 years, 48 in ≥50 years), 21 in patients with non-ischemic cerebrovascular disease and 14 in normal controls were analyzed by enzyme-linked immunosorbent assay The results showed that the positive rate of aCL in patients with cerebral infarction <50 years old and ≥50 years old was significantly higher than that of the control group (all P <0.05), but the positive rate of aCL in patients with cerebral infarction <50 years old was significantly higher than that of> 50 years old Patients (P <0.05). Prompted clinically without any autoimmune disease in young and middle-aged patients with cerebral infarction and aCL more closely.