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【目的】探讨伴有慢性蝶窦炎的垂体瘤经蝶窦显微手术方法 ,如何预防继发颅内感染。【方法】对 15例伴有慢性蝶窦炎的垂体瘤患者施行经蝶窦手术 ,术中完整地剥除蝶窦粘膜 ,打开鞍底前及切瘤后 ,用双氧水、酒精及庆大霉素浸泡蝶窦腔及瘤腔各 2次 ,每次 1min ,X线或导航定位下显微放大 8~ 15倍切瘤 ,切瘤后用链霉素粉肌肉浆封闭鞍底 ,术后加强抗炎3~ 5d。【结果】本组肿瘤全切除 12例 ,次全切除 3例 ,无死亡及其他并发症。【结论】慢性蝶窦炎不应再成为经蝶入路的禁忌症。
[Objective] To investigate the transsphenoidal microsurgery of pituitary tumors with chronic sphenoid sinusitis and how to prevent secondary intracranial infection. 【Methods】 Transsphenoidal sinus surgery was performed on 15 patients with pituitary tumors with chronic sphenoid sinusitis. The sphenoid sinus mucosa was completely removed during the operation. Before open the saddle bottom and after the tumor was cut, use hydrogen peroxide, alcohol, and gentamycin. Soak the sinus cavity and tumor cavity 2 times for 1 min each time. X-ray or navigation positioning microscopically enlarge the tumor 8 to 15 times. After the tumor is cut, use the streptomycin muscle muscle pulp to seal the saddle bottom and strengthen the anti-inflammatory after operation. 3 ~ 5d. 【Results】 In this group, total tumor resection was performed in 12 cases and subtotal resection in 3 cases. There was no death and other complications. [Conclusion] Chronic sphenoiditis should no longer be a contraindication to transsphenoidal approach.