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Objective: To investigate the ratio of chromosomal abnormalities in recurrent fetal wastage. Study design: We conducted a study of the cytogenetic data of 645 couples(1290 patients)-with recurrent fetal wastage examined at the Department of Medical Biology and Genetics, Trabzon, Turkey. Couples who had first trimester miscarriages/abortion, preceded or followed by a second or third trimester fetal death/fetal abnormalities were recruited from Obstetrics and Gynecology Clinics for cytogenetics analysis. Results: Chromosome abnormalities were found in 25(3.86%) patients. The chromosomal abnormalities were structural(3.71%) and numerical(0.15%). Polymorphisms of heterochromatin blocks and inv(9) were shown in 115(17.51%) patients. Conclusions: Chromosome analyses are an important and necessary part of the etiological research in couples with recurrent fetal wastage.
Objective: To investigate the ratio of chromosomal abnormalities in recurrent fetal wastage. Study design: We conducted a study of the cytogenetic data of 645 couples (1290 patients) -with recurrent fetal wastage examined at the Department of Medical Biology and Genetics, Trabzon, Turkey Couples who had first trimester miscarriages / abortion, preceded or followed by a second or third trimester fetal death / fetal abnormalities were recruited from Obstetrics and Gynecology Clinics for cytogenetics analysis. Results: Chromosome abnormalities were found in 25 (3.86%) patients. The Conclusions: Chromosome analyzes are an important and necessary part of the etiological research in couples. The chromosomal abnormalities were structural (3.71%) and numerical (0.15%). Polymorphisms of heterochromatin blocks and inv (9) were shown in 115 with recurrent fetal wastage.