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目的对佛山市南海区首例B群流行性脑脊髓膜炎(简称流脑)病例的流行病学特点进行调查分析,为进一步完善流脑防控策略与措施提供科学依据。方法查阅病例病案,访视病例家属及其他相关知情人,并进行病例的流行病学个案调查。结果患儿邱某某,男性,1岁2个月,于2011年7月11日开始发病,因发热、皮疹就诊并住院治疗,经抗感染、对症支持治疗后好转出院;发病前无与同类患者接触史;家庭居住条件和卫生环境一般;实验室检测证实,该病例为B群脑膜炎奈瑟菌感染;药敏试验显示,病原菌株对替卡西林、哌拉西林、美罗培南、亚胺培南、氨曲南、头孢吡肟、头孢哌酮、头孢他啶、头孢曲松、环丙沙星、左氧氟沙星等均敏感,对复方新诺明、庆大霉素不敏感,对丁胺卡那霉素耐药;经采取综合预防控制措施,未出现二代病例。结论该病例确诊为佛山市南海区首例B群流脑病例,预防控制B群流脑的关键是采取以加强病原学检测、敏感药物使用为重点的综合防控措施。
Objective To investigate the epidemiological characteristics of the first case of meningococcal meningitis group B in Nanhai District of Foshan City, and provide scientific evidence for further improvement of meningococcal prevention and control strategies and measures. Methods Access to medical records, family visits and other relevant insiders, and case epidemiological case studies. Results The patient Qiumoumou, male, 1 year old and 2 months old, began to develop on July 11, 2011. The patient was treated for fever and skin rash and was hospitalized. After anti-infection and symptomatic supportive treatment, he was discharged; History of patient contact; family living conditions and health environment in general; laboratory tests confirmed that the case of Neisseria meningitidis group B infection; susceptibility testing showed that the pathogenic strains of ticarcillin, piperacillin, meropenem, imine Penehyclidine, Aztreonam, Cefepime, Cefoperazone, Ceftazidime, Ceftriaxone, Ciprofloxacin, Levofloxacin and so on were all sensitive to cotrimoxazole and gentamycin. Su-resistant; by taking comprehensive prevention and control measures, did not appear second-generation cases. Conclusions This case was diagnosed as the first case of meningitis B in Nanhai District of Foshan City. The key to prevention and control of meningitis in Group B is to take comprehensive prevention and control measures with emphasis on etiological detection and use of sensitive drugs.