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测定了“鱼血清”对 5种致病菌在营养肉汤中的最低抑菌浓度 (MIC )。结果表明 :“鱼血清”对多数菌的MIC在 0 .1 2 2～ 0 .2 4 4 μg/mL之间 ,说明该药对常见淡水鱼类病原菌有较强的抑制作用。对淡水鱼类细菌性败血症 2株致病菌的体内抗菌活性表明 :采用药浴用量为 3μg/mL ,先给药后感染 ,保护率为 1 0 0 0 %;先感染后给药 ,保护率分别为 60 0 %、83 3%,说明该药对两株菌具有良好的防治作用
The minimum inhibitory concentration (MIC) of “fish serum” on five kinds of pathogenic bacteria in nutrient broth was determined. The results showed that the MIC value of “fish serum” to most of the strains was between 0.212 and 0.244 μg / mL, indicating that the drug had a strong inhibitory effect on common freshwater fish pathogens. In vivo antibacterial activity of two pathogens of bacterial sepsis in freshwater fish showed that: the dosage of medicated bath was 3μg / mL, the first infection after infection, the protection rate was 100%; first infection after administration, the protection rate Respectively, 60 0%, 83 3%, indicating that the drug has a good control of the two strains of bacteria