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目的 回顾性调查我省住院溃疡性结肠炎(UC)患者的诊断、治疗及逐年就诊情况,探讨近年住院病例UC的特点。方法 全省选取5个大型医院,调查1990～2 0 0 3年期间住院诊断为UC的患者,重新审定入组病例,并填写统一的调查表,调查表内容包括患者的诊断、治疗及逐年就诊情况和同期内镜检出率。结果 筛出住院UC患者共3 5 7例,其中男女之比为1.76∶1,年龄12～77(平均46±14 .2 )岁,97.8%UC患者为活动期,以中度(4 2 .7%)和重度(2 9.4%)为主。初发型(3 7.8%)和慢性复发型(4 8.5 %)多见。主要表现为腹泻、腹痛、血便。治疗上以SASP/ 5ASA (69.2 %)和类固醇激素(4 9.0 %)为主。单纯内科治疗总有效率达87.6%,其中8例(2 .2 %)患者行手术治疗,死亡4例(1.1%)。结论 本组住院UC患者以中重度为主,主要为慢性复发型,结肠镜及粘膜活检对诊断有重要意义。综合治疗效果好,预后较好,手术率、病死率及癌变率均较国外报道低。
Objective To retrospectively investigate the diagnosis, treatment and follow-up visits of hospitalized patients with ulcerative colitis (UC) in our province to explore the characteristics of UC in recent years. Methods Five large hospitals were selected throughout the province to investigate patients hospitalized for UC during 1990 ~ 2003 and re-enrolled patients and completed a unified questionnaire, which included the diagnosis, treatment and annual treatment of patients Situation and endoscopic detection rate. Results A total of 377 UC patients were screened out. Among them, the ratio of male to female was 1.76:1, with a mean age of 12-77 (average 46 ± 14.2 years). 97.8% of UC patients were active and moderate (42.2%). 7%) and severe (2 9.4%). Initial onset (3 7.8%) and chronic recurrent (4 8.5%) more common. Mainly for diarrhea, abdominal pain, bloody stools. Treatment with SASP / 5ASA (69.2%) and steroid hormones (9.0%) based. The total effective rate of pure medical treatment was 87.6%, of which 8 (2.2%) were treated surgically and 4 died (1.1%). Conclusion The majority of patients with UC in this group are moderate to severe, mainly chronic recurrent type, colonoscopy and mucosal biopsy are important for the diagnosis. Comprehensive treatment effect is good, the prognosis is good, surgical rate, mortality and canceration rate were lower than foreign reports.