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目的 探讨多发性骨髓瘤 (MM)的临床特征 ,降低误诊率 .方法 分析了 5 5例MM的临床和实验室特征及治疗体会 .结果 年龄大于 5 5岁占 90 .9% ,多数有骨痛、贫血、M蛋白引起的不同程度的肾功能不全 ;血清蛋白电泳出现异常球蛋白峰者占 85 .5 % ;均有骨髓浆细胞增多 ;X线骨损害占 85 .5 % .38例用不同方案化疗 ,2 0例有复查疗效指标 ,其中显效 4例 ,有效 8例 ,无效 8例 ;未化疗 17例 ,全部死亡 ;住院期间死亡 13例确诊时均已属Ⅲ期 .结论 MM临床表现多样化且疗效差 ,为此 ,本文提出及早诊断的线索
Objective To investigate the clinical features of multiple myeloma (MM) and reduce the misdiagnosis rate. Methods The clinical and laboratory characteristics and treatment experience of 55 patients with MM were analyzed. The results were older than 55 years old and accounted for 90.9%. Most of them had bone pain. , Anemia, M protein caused by varying degrees of renal insufficiency; serum protein electrophoresis showed abnormal peaks in the protein were 85.5%; have increased bone marrow plasma cells; X-ray bone damage accounted for 85.5 %. 38 cases with different Under chemotherapy regimens, 20 patients had review efficacy indicators, of which 4 were markedly effective, 8 were effective, and 8 were ineffective; 17 had no chemotherapy and all died; 13 patients who died during hospitalization were all stage III when diagnosed. Conclusions MM has diverse clinical manifestations The results are poor and the results are poor. For this reason, this article proposes clues for early diagnosis.