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光学活性的缩水甘油酸钾（4）是不对称合成的重要试剂。在设计和合成新的神经肌肉阻断剂过程中，用1，6-亚己基二甲磷酸酯和（4）（1：2）在18-冠醚-6和HMPA中反应，分别制得光学活性的对称1，6-亚己基缩水甘油酸酯（6b）和（6c）。不对称的1，6-亚己基二缩水甘油酸酯（6a）的合成分二步进行，首先用（4a）和1，6-亚己基二碳酸酯（1：1）在TEBA和二氯甲烷中反应制得（5），（5）再和（4b）在18-冠醚-6和HMPA中反应制得（6a）。在合成过程中，若将（5）和（4b）在ThBA和二氯甲烷中反应，除得到（6a）外，还得到一个手性的氯代亚己基单缩水甘油酸酯（7）。
Optically active potassium glycidate (4) is an important reagent for asymmetric synthesis. In the design and synthesis of a new neuromuscular blocker, 1,6-hexamethylenephosphate and (4) (1: 2) were reacted in 18-crown-6 and HMPA to produce optical Active symmetrical 1,6-hexylidene glycidate (6b) and (6c). The synthesis of the asymmetric 1,6-hexamethylene diglycidate (6a) was carried out in two steps starting with (4a) and 1,6-hexamethylene dicarbonate (1: 1) in TEBA and dichloromethane (5), (5) and (4b) in 18-crown-6 and HMPA (6a). In the course of the synthesis, chiral hexamethylene monoglycidyl ester (7) is obtained in addition to (6a) if (5) and (4b) are reacted in ThBA and dichloromethane.