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目的分析口服大剂量2.5%等渗甘露醇在多层螺旋CT小肠造影(multislice CTEnterog-raphy,MSCTE)增强扫描中的表现。方法选取30例正常体检者,扫描前30min内分3次口服浓度2.5%的甘露醇2000ml,并肌内注射20mg山莨菪碱(654-2)。然后静脉高压注入优维显100ml后行螺旋CT增强扫描,通过获取多期(20、40、60、120s)横断面及多平面重建(multiplanar reformation,MPR)图像,分别测量小肠各段(十二指肠、空肠、回肠)肠壁与肠腔的CT值以及小肠系膜CT值,进行对比分析。结果小肠充盈均匀,肠腔与肠壁密度对比度好。同一期相中,小肠各段CT值无明显差异(P>0.05);小肠系膜CT值在各期相中无明显差异(P>0.05);小肠肠壁CT值在60s接近峰值,肠腔密度与肠壁密度对比度最佳。结论口服大剂量等渗甘露醇在MSCTE增强扫描中能较好地显示肠壁细微结构及较好地反映肠壁密度,于静脉早期(60S)显示肠壁增强效果最好。
Objective To analyze the performance of oral high dose 2.5% isotonic mannitol in enhanced multislice CTEnterog-raphy (MSCTE) scanning. Methods Thirty healthy subjects were selected. 2000ml of 2.5% mannitol was orally administered orally in three times before the scan, and 20mg of anisodamine (654-2) was injected intramuscularly. Then intravenous high pressure injection of vinorelbine (100ml) was performed and spiral CT enhanced scanning was performed. The multi-period (20, 40, 60, 120s) and multiplanar reconstruction (MPR) The intestine, jejunum, ileum) intestinal wall and intestine CT value and small intestine CT value, comparative analysis. The results of uniform filling the small intestine, intestine and bowel wall density contrast is good. In the same phase, there was no significant difference in the CT value of each segment of small intestine (P> 0.05). The small intestine CT value had no significant difference in each phase (P> 0.05) Density and bowel wall density contrast the best. Conclusion The oral administration of high-dose isotonic mannitol can better display the intestinal wall microstructure and better reflect the intestinal wall density in MSCTE enhanced scanning. The enhancement of intestinal wall in the early stage of vein (60S) is the best.