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目的分析我院近3年48例假单胞菌肺部感染病例,以探讨其临床特点、药敏试验及预后。方法:按假单胞菌肺部感染诊断标准诊断,进行痰培养、药物试验;结果:有基础疾病者36例(75.00%),其中以慢性阻塞性肺部疾病多见(41.67%);单纯肺部感染12例(25.00%)。痰培养结果为绿脓杆菌35例(72.93%),其它假单胞菌15例(28.30%)。最敏感药物为环丙沙星(97.37%),其次是丁胺卡那霉素(96.15%);对氨苄青霉素100%耐药。治愈及好转共26例(54.17%);无效22例(45.83%),其中死亡12例,病死率25.00%。结论:假单胞菌性肺部感染患者与有否基础疾病、患者年龄及所感染假单胞菌类型有关
Objective To analyze 48 cases of Pseudomonas aeruginosa pulmonary infection in our hospital in recent 3 years to investigate their clinical features, drug sensitivity test and prognosis. Methods: According to diagnostic criteria of Pseudomonas aeruginosa lung infection, sputum culture and drug test were performed. Results: Thirty-six patients (75.00%) had underlying diseases, of which chronic obstructive pulmonary disease was common (41.67 %); Simple pulmonary infection in 12 cases (25.00%). Results of sputum culture were Pseudomonas aeruginosa in 35 cases (72.93%) and other Pseudomonas in 15 cases (28.30%). The most sensitive drugs were ciprofloxacin (97.37%), followed by amikacin (96.15%); resistant to ampicillin 100%. Twenty-six cases (54.17%) were cured and improved, 22 cases (45.83%) were ineffective, including 12 deaths and a mortality rate of 25.00%. CONCLUSIONS: Pseudomonas aeruginosa infections are associated with underlying disease, patient age, and the type of Pseudomonas infection