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肿瘤血管生成或肿瘤内血管形成对癌细胞的存活、局部肿瘤的生长和远处转移起重要作用,新生血管可向生长肿瘤提供充足的氧气和营养,并促进浸润和转移。没有小血管供给新生肿瘤细胞所需营养,肿瘤生长不可能超过2~3mm3。血管生长因子的合成和分泌在肿瘤生长和扩散中起重要作用,在?
Tumor angiogenesis or intratumoral angiogenesis plays an important role in the survival of cancer cells, local tumor growth and distant metastasis. Neovascularization provides sufficient oxygen and nutrients to the growing tumor and promotes infiltration and metastasis. No small blood vessels to supply the nutrients required for new tumor cells, tumor growth can not exceed 2 ~ 3mm3. The synthesis and secretion of vascular growth factor plays an important role in the growth and spread of tumors.