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骨髓间充质干细胞是一种成体干细胞,是组织工程的重要种子细胞之一。它来源丰富,取材方便,不但具有自我更新和多向分化的性质,还具有明显的可塑性特性。研究显示骨髓间充质干细胞可应用于多种疾病的治疗。本文就骨髓间充质干细胞的性质、分离方法、可塑性及其在肾脏中的应用做一简要综述。
Bone marrow mesenchymal stem cells are adult stem cells and one of the important seed cells for tissue engineering. It is rich in source, easy access, not only has the nature of self-renewal and multi-directional differentiation, but also has obvious plasticity characteristics. Studies have shown that bone marrow mesenchymal stem cells can be applied to the treatment of many diseases. This article summarizes the properties of bone marrow mesenchymal stem cells, isolation methods, plasticity and their application in the kidney.