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目的观察痰热清注射液联合抗菌药物治疗肺癌化疗后肺部感染的临床疗效。方法选取2014年1月—2016年1月四川绵阳四0四医院收治的肺癌化疗后合并肺部感染患者52例,根据随机数字表法分为观察组和对照组,各26例。对照组患者化疗后单纯给予头孢唑肟治疗,观察组患者在对照组基础上联用痰热清注射液治疗。比较两组患者临床疗效、胸部X线有效改善率及症状缓解时间。结果观察组患者临床疗效优于对照组,胸部X线有效改善率高于对照组,发热缓解时间、肺部啰音消失时间、咳嗽咳痰减少时间均短于对照组(P<0.05)。结论痰热清注射液联合抗菌药物治疗肺癌化疗后肺部感染的临床疗效确切,并能缩短疗程。
Objective To observe the clinical effect of Tanreqing Injection and antimicrobial agents in treatment of pulmonary infection after chemotherapy for lung cancer. Methods From January 2014 to January 2016, 52 patients with pulmonary infection after lung cancer chemotherapy were enrolled in Si44 Hospital of Mianyang, Sichuan Province. According to the random number table, the patients were divided into observation group and control group, with 26 cases in each group. Patients in the control group were treated with ceftizoxime only after chemotherapy, and patients in the observation group were treated with Tanreqing Injection on the basis of the control group. The clinical efficacy, effective rate of chest X-ray and symptom relief were compared between the two groups. Results The clinical efficacy of the observation group was better than that of the control group. The improvement rate of chest X-ray was higher than that of the control group. The time of fever relief, the time of pulmonary rales disappearing, and the cough and expectoration time were shorter than those of the control group (P <0.05). Conclusion Tanreqing injection combined with antibacterial drugs in the treatment of pulmonary infection after lung cancer clinical curative effect is exact and can shorten the course of treatment.