Mapping of quantitative trait loci using the skew-normal distribution

• 作 者: FERNANDES Elisabete PACHECO An
• 机 构: CentreforMathematicsandltsApplications,DepartmentofStatisticsandOperationalResearch,DepartmentofMath
• 出 处: 浙江大学学报：B卷英文版
• 发表日期: 2007年11期
• 关键词: 区间映射 数量性状 期望最大值算法 分布状况 Interval mapping （IM） Quantitative trait loci （QTL） Ske
• 基金项目: Project supported in part by Foundation for Science and Technology （FCT） （No. SFRD/BD/5987/2001）, and the 0perational Program Science, Technology, and Innovation of the FCT, co-financed by the Europea

In standard interval mapping (IM) of quantitative trait loci (QTL), the QTL effect is described by a normal mixture model. When this assumption of normality is violated, the most commonly adopted strategy is to use the previous model after data transforma