Anti-HBV effect of TAT- HBV targeted ribonuclease

• 作 者: JinDing JunLiu Cai-FangXue Wei
• 机 构: DepartmentofEtiology
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2003年7期
• 关键词: 乙型肝炎病毒 核糖核酸酶 TAT融合蛋白 蛋白纯化
• 基金项目: 国家自然科学基金，国家医学科研项目，Innovation Project of FMMU

AIM: To prepare and purify TAT-HBV targeted ribonuclease fusion protein, evaluate its transduction activity and investigate its effect on HBV replication in 2.2.15 cells.METHODS: The prokaryotic expression vector pTAT containing TR gene was used in transf